Title : Aminoacetyl moiety as a potential surrogate for diacylhydrazine group of SC-51089, a potent PGE2 antagonist, and its analogs.

Pub. Date : 1996 Jan 19

PMID : 8558534






1 Functional Relationships(s)
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1 Analogs of SC-51089, in which the diacylhydrazine functionality has been replaced by isosteric and isoelectronic groups, have been synthesized and have been shown to be analgesics and PGE2 antagonists of the EP1 subtype. Dinoprostone prostaglandin E receptor 1 Rattus norvegicus