Title : Transgenic mice expressing the human high-affinity immunoglobulin (Ig) E receptor alpha chain respond to human IgE in mast cell degranulation and in allergic reactions.

Pub. Date : 1996 Jan 1

PMID : 8551243






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cross-linking of the transgenic Fc epsilon RI with human IgE and antigens led to mast cell activation as indicated by enhanced tyrosine phosphorylation of the Fc epsilon RI beta and gamma chains and other cellular proteins. Tyrosine membrane spanning 4-domains A1 Homo sapiens