Title : Calcium and calmodulin regulate lipopolysaccharide-induced alveolar macrophage production of tumor necrosis factor and procoagulant activity.

Pub. Date : 1996 Jan

PMID : 8546576






2 Functional Relationships(s)
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1 Either W7 (20 mumol/L), a calmodulin antagonist, or TMB-8 (50 mumol/L), which prevents calcium release from the endoplasmic reticulum, inhibited production of both TNF and PC activity. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate tumor necrosis factor Homo sapiens
2 Verapamil (50 mumol/L) alone or combined with TMB-8 significantly inhibited both TNF and PC production by LPS-stimulated M phi. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate tumor necrosis factor Homo sapiens