Title : A mutation affecting carbon catabolite repression suppresses growth defects in pyruvate carboxylase mutants from Saccharomyces cerevisiae.

Pub. Date : 1995 Dec 18

PMID : 8543050






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The BPC1-1 mutation abolishes catabolite repression of a series of genes and allows expression of the enzymes of the glyoxylate cycle during growth in glucose. glyoxylic acid Mth1p Saccharomyces cerevisiae S288C
2 A functional glyoxylate cycle is necessary for suppression as a disruption of gene ICL1 encoding isocitrate lyase abolished the phenotypic effect of BPC1-1 on growth in glucose-ammonium. glyoxylic acid Mth1p Saccharomyces cerevisiae S288C