Pub. Date : 1995 Nov 27
PMID : 8521977
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The regulation of apolipoprotein A-I (apo A-I) gene expression by 12-O-tetradecanoylphorbol 13-acetate (TPA) was investigated in the human hepatoma cell line Hep G2. | Tetradecanoylphorbol Acetate | apolipoprotein A1 | Homo sapiens |
| 2 | The regulation of apolipoprotein A-I (apo A-I) gene expression by 12-O-tetradecanoylphorbol 13-acetate (TPA) was investigated in the human hepatoma cell line Hep G2. | Tetradecanoylphorbol Acetate | apolipoprotein A1 | Homo sapiens |
| 3 | The regulation of apolipoprotein A-I (apo A-I) gene expression by 12-O-tetradecanoylphorbol 13-acetate (TPA) was investigated in the human hepatoma cell line Hep G2. | Tetradecanoylphorbol Acetate | apolipoprotein A1 | Homo sapiens |
| 4 | The regulation of apolipoprotein A-I (apo A-I) gene expression by 12-O-tetradecanoylphorbol 13-acetate (TPA) was investigated in the human hepatoma cell line Hep G2. | Tetradecanoylphorbol Acetate | apolipoprotein A1 | Homo sapiens |
| 5 | TPA treatment decreased apo A-I mRNA levels in a time-dependent manner, by up to 50% versus control cells within 24 h. Nuclear run-on transcription assays demonstrated a transcriptional effect of TPA. | Tetradecanoylphorbol Acetate | apolipoprotein A1 | Homo sapiens |
| 6 | TPA treatment decreased apo A-I mRNA levels in a time-dependent manner, by up to 50% versus control cells within 24 h. Nuclear run-on transcription assays demonstrated a transcriptional effect of TPA. | Tetradecanoylphorbol Acetate | apolipoprotein A1 | Homo sapiens |
| 7 | Using transfection analysis with a plasmid construct containing the -1378/+11 apo A-I promoter fused to the secreted placental alkaline phosphatase (SPAP) reporter gene, we showed that the SPAP activity was decreased to 50% when Hep G2 cells were incubated in the presence of TPA. | Tetradecanoylphorbol Acetate | apolipoprotein A1 | Homo sapiens |
| 8 | The inhibitory effect of TPA was still maintained when fragment -253 to -4 of apo A-I promoter was linked to the CAT reporter gene. | Tetradecanoylphorbol Acetate | apolipoprotein A1 | Homo sapiens |