Title : Role of prostaglandins in the control of renin secretion in the dog.

Pub. Date : 1977 May

PMID : 852103






4 Functional Relationships(s)
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1 Infusion of indomethacin into anesthetized, salt-depleted dogs cuased an increase in mean arterial blood pressure (MABP), and decreases in heart rate (HR), urine flow rate (V), renal plasma flow (RPF), and renin secretion rate. Indomethacin renin Canis lupus familiaris
2 Renin secretion rate decreased from 1,194.1 +/- 353.9 U/min during control periods to reach 384.0 +/- 125.8 U/min (P less than 0.025) by 80 minutes of infusion of indomethacin. Indomethacin renin Canis lupus familiaris
3 The decrease in renin secretion rate during the infusion of indomethacin persisted when renal perfusion pressure (RPP) was maintained relatively constant before and during the infusion of indomethacin. Indomethacin renin Canis lupus familiaris
4 The decrease in renin secretion rate during the infusion of indomethacin persisted when renal perfusion pressure (RPP) was maintained relatively constant before and during the infusion of indomethacin. Indomethacin renin Canis lupus familiaris