Title : Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages.

Pub. Date : 1993 Jul

PMID : 8510229






2 Functional Relationships(s)
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1 Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages. phosphorothioate oligodeoxynucleotides Vpr Human immunodeficiency virus 1
2 We synthesized five antisense phosphorothioate oligodeoxynucleotides complementary to the vpr mRNA of HIV-1Ba-L, a highly macrophage-tropic viral strain, and measured their effect on HIV-1Ba-L replication in primary human macrophages. phosphorothioate oligodeoxynucleotides Vpr Human immunodeficiency virus 1