Pub. Date : 1993 May
PMID : 8504036
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cholesterol and sphingolipid synthesis are regulated by the rate-limiting enzymes HMG CoA reductase and serine palmitoyl transferase (SPT), respectively. | Sphingolipids | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |
| 2 | Topical application of HMG CoA reductase or SPT inhibitors after acetone treatment delays barrier repair, providing further evidence for a role of cholesterol and sphingolipids in epidermal barrier function. | Sphingolipids | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |