Title : Molecular size and flexibility as determinants of selectivity in the oxidation of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs by monoamine oxidase A and B.

Pub. Date : 1993 Apr 30

PMID : 8487265






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The introduction of a methylene bridge between the phenyl and tetrahydropyridyl moieties of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) results in increased selectivity for monoamine oxidase B (MAO B) over monoamine oxidase A (MAO A). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine monoamine oxidase B Homo sapiens
2 The introduction of a methylene bridge between the phenyl and tetrahydropyridyl moieties of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) results in increased selectivity for monoamine oxidase B (MAO B) over monoamine oxidase A (MAO A). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine monoamine oxidase B Homo sapiens
3 The introduction of a methylene bridge between the phenyl and tetrahydropyridyl moieties of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) results in increased selectivity for monoamine oxidase B (MAO B) over monoamine oxidase A (MAO A). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine monoamine oxidase B Homo sapiens
4 The introduction of a methylene bridge between the phenyl and tetrahydropyridyl moieties of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) results in increased selectivity for monoamine oxidase B (MAO B) over monoamine oxidase A (MAO A). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine monoamine oxidase B Homo sapiens