Pub. Date : 1993 May 15
PMID : 8486725
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the presence of NADPH and NADPH-P450 reductase some reduction to N,N-dialkylamines occurred, along with N-dealkylation (to monoalkylanilines); there was also slow N-dealkylation in the absence of NADPH, which is interpreted in terms of homolytic scission of the N-O bond; N,N-dialkylanilines were not formed nor did the N-oxides support other oxygenation reactions. | n-oxides | 2,4-dienoyl-CoA reductase 1 | Homo sapiens |
| 2 | In the presence of NADPH and NADPH-P450 reductase some reduction to N,N-dialkylamines occurred, along with N-dealkylation (to monoalkylanilines); there was also slow N-dealkylation in the absence of NADPH, which is interpreted in terms of homolytic scission of the N-O bond; N,N-dialkylanilines were not formed nor did the N-oxides support other oxygenation reactions. | n-oxides | 2,4-dienoyl-CoA reductase 1 | Homo sapiens |
| 3 | In the presence of NADPH and NADPH-P450 reductase some reduction to N,N-dialkylamines occurred, along with N-dealkylation (to monoalkylanilines); there was also slow N-dealkylation in the absence of NADPH, which is interpreted in terms of homolytic scission of the N-O bond; N,N-dialkylanilines were not formed nor did the N-oxides support other oxygenation reactions. | n-oxides | 2,4-dienoyl-CoA reductase 1 | Homo sapiens |
| 4 | P450 2B1 (with its reductase and NADPH) formed N-oxides at low rates from several N,N-dialkylaniline derivatives, including N,N-dimethylaniline, N,N-diethylaniline, N-ethyl-N-methylaniline, 4-methyl-N,N-dimethylaniline, 4-cyano-N,N-dimethylaniline, N-phenylpyrrolidine, and N,N-dimethyl-2-aminofluorene. | n-oxides | 2,4-dienoyl-CoA reductase 1 | Homo sapiens |