Title : The metabolism of aprindine in relation to the sparteine/debrisoquine polymorphism.

Pub. Date : 1993 Apr

PMID : 8485023






1 Functional Relationships(s)
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1 AP was found to be a competitive inhibitor of CYP2D6 as indicated by its ability to impair the formation of (2S)-hydroxysparteine, 5,6-didehydrosparteine and 5-hydroxypropafenone by human liver microsomes. 5-hydroxypropafenone cytochrome P450 family 2 subfamily D member 6 Homo sapiens