Title : Cytogenetic effects of promutagens in genetically engineered V79 Chinese hamster cells expressing cytochromes P450.

Pub. Date : 1993 Apr 1

PMID : 8482321






1 Functional Relationships(s)
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1 A significant sister chromatid exchange inducing effect was found after a 24 h exposure in each of the genetically engineered cell lines, except for benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in CYP2B1 expressing cells, and for benzo[a]pyrene in cells expressing both CYP1A2 and acetyltransferase. anthracene cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus