Title : Gastrin and CCK activate phospholipase C and stimulate pepsinogen release by interacting with two distinct receptors.

Pub. Date : 1993 Apr

PMID : 8476056






2 Functional Relationships(s)
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1 Both CCK-8 and gastrin increased inositol phosphates, with CCK-8 (1 microM) and gastrin (3 microM) causing a 40- and 14-fold increase in [3H]IP1, 10- and 6-fold for [3H]IP2, and 8- and 4-fold for [3H]IP3. Inositol 1,4,5-Trisphosphate gastrin Homo sapiens
2 Both CCK-8 and gastrin increased inositol phosphates, with CCK-8 (1 microM) and gastrin (3 microM) causing a 40- and 14-fold increase in [3H]IP1, 10- and 6-fold for [3H]IP2, and 8- and 4-fold for [3H]IP3. Inositol 1,4,5-Trisphosphate gastrin Homo sapiens