Title : Gene inactivation in Lec35.1 (mannosylation-defective) Chinese hamster ovary cells. A cautionary note.

Pub. Date : 1993 Mar 25

PMID : 8454645






1 Functional Relationships(s)
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1 Interestingly, these results suggest similarities between the Lec35.1 defect and the human disease paroxysmal nocturnal hemoglobinuria, which may involve gradual inactivation of a gene necessary for mannosylation of GPI anchor precursors. Glycosylphosphatidylinositols mannose-P-dolichol utilization defect 1 Homo sapiens