Title : Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.

Pub. Date : 1993 Mar 25

PMID : 8454631






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Among common NSAIDs tested, indomethacin, sulindac sulfide, and piroxicam preferentially inhibited PGH synthase-1; ibuprofen, flurbiprofen, and meclofenamate inhibited both enzymes with comparable potencies; and 6-methoxy-2-naphthylacetic acid preferentially inhibited PGH synthase-2. Piroxicam prostaglandin-endoperoxide synthase 1 Mus musculus