Title : Cardiotoxic effects of nitrofurantoin and tertiary butylhydroperoxide in vitro: are oxygen radicals involved?

Pub. Date : 1993 Jan

PMID : 8441741






1 Functional Relationships(s)
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1 Addition of catalase (100 mU/ml) or catechin (0.5 mmol/l) to the perfusion medium abolished the nitrofurantoin induced release of oxidized glutathione but did not not prevent or attenuate enzyme leakage from the cells and the development of a negative inotropic effect. Nitrofurantoin catalase Rattus norvegicus