Title : Protective effect of calmodulin inhibitors against acute cyanide-induced lethality and convulsions in mice.

Pub. Date : 1993 Jan

PMID : 8427023






1 Functional Relationships(s)
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1 Since it is known that the inhibitory effect of TFP or CHP against calmodulin-dependent enzymes such as phosphodiesterase is 100-400-fold higher compared to PMZ, it is speculated that the inhibitory effect of TFP or CHP against cyanide-induced convulsions may be based on its strong inhibitory properties into calmodulin-dependent enzymes. Promethazine calmodulin 2 Mus musculus