Title : Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase.

Pub. Date : 1993 Jan 1

PMID : 8419946






1 Functional Relationships(s)
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1 Inhibition of squalene synthase in cells and in vivo was accompanied by an accumulation of label from [3H]mevalonate into farnesyl diphosphate, farnesol, and organic acids. farnesyl pyrophosphate farnesyl-diphosphate farnesyltransferase 1 Homo sapiens