Title : The NMDA receptor antagonist MK-801 markedly reduces the induction of c-fos gene by haloperidol in the mouse striatum.

Pub. Date : 1993 Jun 25

PMID : 8414186






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1 The NMDA receptor antagonist MK-801 markedly reduces the induction of c-fos gene by haloperidol in the mouse striatum. Haloperidol FBJ osteosarcoma oncogene Mus musculus
2 The influence of the N-methyl-D-aspartate (NMDA) receptor antagonist, MK-801 (dizocilpine), on the haloperidol-induced increase of c-fos mRNA levels in the striata of mice was examined using the quantitative Northern blot analysis method. Haloperidol FBJ osteosarcoma oncogene Mus musculus
3 Higher doses of MK-801 (1.5-4.5 mg/kg) diminished c-fos mRNA increase produced by haloperidol by 80%. Haloperidol FBJ osteosarcoma oncogene Mus musculus