Title : Glycosphingolipid inhibition of the adhesion of thrombin-activated platelets to surfaces is potentiated by albumin.

Pub. Date : 1993 Aug

PMID : 8400548






1 Functional Relationships(s)
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1 Previous studies have shown that exogenous glycosphingolipids (GSLs) inhibit the adhesion of thrombin-activated platelets (TAP) to polystyrene plates coated with various RGD-ligands (where RGD is the peptide sequence Arg-Gly-Asp), suggesting that GSLs can modulate the platelet integrin receptor glycoprotein IIb-IIIa. Glycine coagulation factor II, thrombin Bos taurus