Pub. Date : 1993 Aug
PMID : 8396340
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Using primary cultures of mouse renal JG cells, we found that sodium nitroprusside (SNP) and 3-morpholino-sydnonimin-hydrochloride (SIN-1), two structurally different liberators of NO, led to a transient inhibition during the first hour followed by a marked dose-dependent stimulation of renin secretion lasting for an additional 20 h. This stimulatory effect was blunted by methylene blue (50 microM) and was reversible within minutes after removal of the NO liberators. | Methylene Blue | mitogen-activated protein kinase associated protein 1 | Mus musculus |