Title : A mutation (Trp1193-->Leu1193) in the tyrosine kinase domain of the insulin receptor associated with type A syndrome of insulin resistance.

Pub. Date : 1993 May

PMID : 8390949






1 Functional Relationships(s)
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1 On examination, the biological activities of insulin and insulin-like growth factor I in the patient"s cultured fibroblasts, insulin sensitivity of amino isobutyric acid uptake and thymidine incorporation was decreased, but insulin-like growth factor I action was normal. Aminoisobutyric Acids insulin like growth factor 1 Homo sapiens