Title : Activation of myelin basic protein and S6 peptide kinases in phorbol ester- and PAF-treated sheep platelets.

Pub. Date : 1993 Apr 16

PMID : 8385998






3 Functional Relationships(s)
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1 Treatment of platelets with 200 nM 12-O-tetradecanoylphorbol-13-acetate (PMA) led to 5-fold stimulations of cytosolic MBP and S6 peptide kinase activities within 1 min. Tetradecanoylphorbol Acetate myelin basic protein Ovis aries
2 Treatment of platelets with 200 nM 12-O-tetradecanoylphorbol-13-acetate (PMA) led to 5-fold stimulations of cytosolic MBP and S6 peptide kinase activities within 1 min. Tetradecanoylphorbol Acetate myelin basic protein Ovis aries
3 Immunoblotting analysis of phenyl-Superose-fractionated cytosol from PMA-treated platelets with a panel of mitogen-activated protein (MAP) kinase anti-peptide antibodies revealed that one of the activated MBP kinases was p42mapk. Tetradecanoylphorbol Acetate myelin basic protein Ovis aries