Title : Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans.

Pub. Date : 1993 Mar 1

PMID : 8383325






1 Functional Relationships(s)
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1 Higher concentrations (IL-1 beta at 75 units/ml, 3.5 nM TNF-alpha, and IFN-gamma at 750 units/ml) inhibit insulin secretion from human islets, and the inhibitory effect is prevented by NG-monomethyl-L-arginine. omega-N-Methylarginine tumor necrosis factor Homo sapiens