Title : Diamine oxidase activity in rat brain carcinogenesis and in gliomas.

Pub. Date : 1993 Jul 30

PMID : 8364892






2 Functional Relationships(s)
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1 In the early stages of brain carcinogenesis induced by transplacental administration of N-ethyl-N-nitrosourea to BD IX rats, a constant increase in the activity of cerebral diamine oxidase, the rate-limiting enzyme in terminal catabolism of polyamines, was observed. Polyamines amine oxidase, copper containing 1 Rattus norvegicus
2 Such findings indicate that an increase in oxidative putrescine catabolism via diamine oxidase takes place in transformed cells and in gliomas and is probably linked to an activation of polyamine synthesis and turnover. Polyamines amine oxidase, copper containing 1 Rattus norvegicus