Title : Platelet-derived microparticle formation involves glycoprotein IIb-IIIa. Inhibition by RGDS and a Glanzmann's thrombasthenia defect.

Pub. Date : 1993 Jul 15

PMID : 8325838






1 Functional Relationships(s)
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1 We demonstrate using flow cytometric methods a central role for the beta 3 integrin glycoprotein (GP) IIb-IIIa complex and its ligand tetrapeptide Arg-Gly-Asp-Ser (RGDS) binding site in platelet vesiculation. Arginine ral guanine nucleotide dissociation stimulator Homo sapiens