Title : Bradykinin release of TNF-alpha plays a key role in the development of inflammatory hyperalgesia.

Pub. Date : 1993

PMID : 8317326






1 Functional Relationships(s)
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1 Using specific antisera for IL-1 beta and IL-8, as well as cyclooxygenase inhibitors and propranolol, we have demonstrated that these cytokines are responsible for the prostaglandin and sympathetic components of carrageenin-induced hyperalgesia in the rat paw test. Carrageenan interleukin 1 beta Rattus norvegicus