Pub. Date : 1994 Jan
PMID : 8311478
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Porin proteins in mitochondria from rat pancreatic islet cells and white adipocytes: identification and regulation of hexokinase binding by the sulfonylurea glimepiride. | glimepiride | hexokinase | Saccharomyces cerevisiae S288C |
2 | These data suggest that the sulfonylurea glimepiride, which is thought to inhibit the ATP-regulated K(+)-channel in beta-cells, may have, in addition, an intracellular site of action in pancreatic islet and adipocyte cells at the level of regulation of gluco-/hexokinase binding to mitochondrial porin. | glimepiride | hexokinase | Saccharomyces cerevisiae S288C |