Pub. Date : 1994 Feb 11
PMID : 8308013
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Only thioglycollate-elicited macrophages express cell surface Mac-2, and binding is mostly (> 80%) a result of affinity for cell surface carbohydrate structures. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |
| 2 | Mac-2 surface expression is markedly reduced upon further activation of thioglycollate-elicited macrophages with bacterial lipopolysaccharide in vitro. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |
| 3 | Chemical cross-linking experiments have identified binding of endogenous cell-surface Mac-2 to three glycoproteins of molecular masses of 92, 125, and 180 kDa containing alpha-galactosyl and polylactosamine structures on thioglycollate-elicited macrophages. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |
| 4 | The restricted cell surface distribution of Mac-2 on thioglycollate-elicited peritoneal macrophages, a population of recently recruited monocytes, suggests a role(s) in early events of macrophage infiltration and tissue fixation such as extravasion and cell-matrix interactions. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |