Title : Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells.

Pub. Date : 1993 Jul 1

PMID : 8281294






1 Functional Relationships(s)
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1 Here we provide evidence that interferon-gamma (IFN-gamma), interleukin (IL)-1 beta and tumour necrosis factor-alpha induce L-arginine-dependent cyclic GMP synthesis in C6 cells and that a combination of IFN-gamma and IL-1 beta induce L-arginine-dependent cyclic GMP synthesis in astrocyte cultures, indicating that these cytokines induce NOS. Arginine interleukin 1 beta Rattus norvegicus