Title : Complement activation upon binding of mannan-binding protein to HIV envelope glycoproteins.

Pub. Date : 1993 Oct

PMID : 8267903






2 Functional Relationships(s)
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1 RESULTS: Complement activation by HIV envelope glycoproteins was found to be mediated by the binding of MBP to carbohydrates on natural envelope protein produced in virus-infected cells, as well as on glycosylated recombinant envelope proteins produced in insect cells. Carbohydrates myelin basic protein Homo sapiens
2 CONCLUSIONS: Activation of the classical complement pathway by retrovirus envelope proteins can be initiated by the binding of MBP to carbohydrate side chains of envelope glycoproteins. Carbohydrates myelin basic protein Homo sapiens