Title : UDP glucuronosyltransferase gene expression is involved in the stimulation of ascorbic acid biosynthesis by xenobiotics in rats.

Pub. Date : 1993 Dec

PMID : 8263600






2 Functional Relationships(s)
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1 In rats of both genotypes, the activity and hepatic concentration of chloramphenicol-UDPGT mRNA and liver and urine ascorbic acid concentration were increased by sodium phenobarbital. Phenobarbital UDP glycosyltransferase 2 family, polypeptide B Rattus norvegicus
2 The data indicate that the stimulation of the expression of both the 4-nitrophenol and chloramphenicol UDPGT genes plays a key role in the ascorbic acid biosynthesis induced by 3MC and sodium phenobarbital. Phenobarbital UDP glycosyltransferase 2 family, polypeptide B Rattus norvegicus