Pub. Date : 1993 Dec
PMID : 8246999
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A mutant androgen receptor from patients with Reifenstein syndrome: identification of the function of a conserved alanine residue in the D box of steroid receptors. | Alanine | androgen receptor | Homo sapiens |
| 2 | Exchanging alanine 596 in the wild-type androgen receptor with serine or valine produced mutants with properties indistinguishable from those of the naturally occurring threonine 596 mutant receptor. | Alanine | androgen receptor | Homo sapiens |
| 3 | These results indicate that an alanine residue at position 596 contributes important structural and functional activities to the androgen receptor. | Alanine | androgen receptor | Homo sapiens |
| 4 | In the androgen receptor from the patients with Reifenstein syndrome, in which this alanine is converted to a threonine, wild-type receptor properties can be restored by exchanging an additional threonine at position 602 to an alanine. | Alanine | androgen receptor | Homo sapiens |
| 5 | An alanine residue at position 596 or 602 in the DNA binding domain of the androgen receptor is therefore important for the full function of this receptor. | Alanine | androgen receptor | Homo sapiens |
| 6 | In all steroid receptors that bind the core sequence AGAACANNNTGTTCT, an alanine residue is also present at a position equivalent to alanine 596 in the androgen receptor. | Alanine | androgen receptor | Homo sapiens |
| 7 | In all steroid receptors that bind the core sequence AGAACANNNTGTTCT, an alanine residue is also present at a position equivalent to alanine 596 in the androgen receptor. | Alanine | androgen receptor | Homo sapiens |