Title : Endogenous nitric oxide protects against platelet-activating factor-induced bowel injury in the rat.

Pub. Date : 1993 Aug

PMID : 8233729






1 Functional Relationships(s)
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1 Compared with animals given PAF alone, animals pretreated with L-NAME followed by PAF developed significantly worse bowel injury (median injury scores: 2.5 versus 0.5, p = 0.005), hemoconcentration (final hematocrit 65.2 +/- 2.0% versus 53.9 +/- 1.0%, p < 0.001), and intestinal myeloperoxidase activity (12.45 +/- 1.94 U/g versus 6.51 +/- 0.57 U/g, p < 0.01). NG-Nitroarginine Methyl Ester PCNA clamp associated factor Rattus norvegicus