Title : Artificial duplication of the R67 dihydrofolate reductase gene to create protein asymmetry. Effects on protein activity and folding.

Pub. Date : 1993 Oct 25

PMID : 8226776






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The protein product, R67 DHFRdouble, is twice the molecular mass of native R67 DHFR and is fully active with kcat = 1.2 s-1, Km(NADPH) = 2.7 microM and Km(dihydrofolate) = 6.3 microM. dihydrofolate dihydrofolate reductase Homo sapiens