Title : Synthesis of prolyl endopeptidase inhibitors and evaluation of their structure-activity relationships: in vitro inhibition of prolyl endopeptidase from canine brain.

Pub. Date : 1993 Sep

PMID : 8221972






1 Functional Relationships(s)
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1 Among them, 4-(2-thienyl)butanoyl derivatives (V-24--27) showed more potent PEP-inhibitory activity than SUAM-1221. 4-(2-thienyl)butanoyl derivatives prolyl endopeptidase Canis lupus familiaris