Title : The N-terminal domain of human urokinase receptor contains two distinct regions critical for ligand recognition.

Pub. Date : 1993 Nov 1

PMID : 8219225






1 Functional Relationships(s)
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1 Within this region, the mu-PAR domain 1 could be minimally humanized to bind human pro-u-PA by a substitution of as few as four of the six nonconserved residues, thereby identifying the residues arginine-2, lysine-7, threonine-8, and glycine-10 as important in determining binding specificity. Threonine jumping translocation breakpoint Homo sapiens