Title : Effects of transforming growth factor-beta on human fetal adrenal steroid production.

Pub. Date : 1994 Mar

PMID : 8206321






3 Functional Relationships(s)
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1 Inhibition of basal dehydroepiandrosterone sulfate (DS) production usually was noted only after 3 or more days of treatment with > or = 0.1 ng TGF-beta/ml. Dehydroepiandrosterone Sulfate transforming growth factor beta 1 Homo sapiens
2 Inhibition of basal dehydroepiandrosterone sulfate (DS) production usually was noted only after 3 or more days of treatment with > or = 0.1 ng TGF-beta/ml. Dehydroepiandrosterone Sulfate transforming growth factor beta 1 Homo sapiens
3 These results are suggestive that TGF-beta differentially inhibits DS and cortisol production by human fetal adrenal cells and that the site of TGF-beta action on steroidogenesis may be distal to the generation of cAMP. Dehydroepiandrosterone Sulfate transforming growth factor beta 1 Homo sapiens