Title : Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancers.

Pub. Date : 1994 Jun 1

PMID : 8187068






1 Functional Relationships(s)
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1 Direct sequencing of the polymerase chain reaction-derived DNAs of 6 of 24 specimens revealed a codon 877 mutation (ACT-->GCT, Thr-->Ala) in the hormone-binding domain of the AR gene. Alanine androgen receptor Homo sapiens