Title : Protein kinase C inhibitors suppress LPS-induced TNF production in alveolar macrophages and in whole blood: the role of encapsulation into liposomes.

Pub. Date : 1994 May 26

PMID : 8186258






1 Functional Relationships(s)
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1 We studied the effect of two PKC inhibitors, staurosporine (STP) and sphingosine (SPG), on TNF production in rat alveolar macrophages (AM) and in whole blood (BM) incubated with 0.25-25,000 ng/ml of LPS. Sphingosine tumor necrosis factor-like Rattus norvegicus