Pub. Date : 1994 May 19
PMID : 8183344
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA. | Cyclosporine | interleukin 3 | Homo sapiens |
| 2 | Transcripts from exogenous IL-3 genes lacking the (A+U)-rich element (ARE) in the 3" untranslated terminal repeat could not be destabilized, suggesting that at least part of this sequence, which is known to mediate decay of short-lived mRNA, participates in a CsA-sensitive regulatory mechanism. | Cyclosporine | interleukin 3 | Homo sapiens |