Title : Effects of chronic phorbol ester treatment on protein kinase C activity, content, and gene expression in the human monoblastoid U937 cell.

Pub. Date : 1994 Feb

PMID : 8180129






7 Functional Relationships(s)
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Protein Name
Organism
1 AP-1 binding activity was enhanced by 12-O-tetradecanoylphorbol-13-acetate (TPA) and in a temporally dependent manner, with conversion of a high to low mobility band shift occurring after a 12-h exposure to TPA. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 AP-1 binding activity was enhanced by 12-O-tetradecanoylphorbol-13-acetate (TPA) and in a temporally dependent manner, with conversion of a high to low mobility band shift occurring after a 12-h exposure to TPA. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
3 AP-1 binding activity was enhanced by 12-O-tetradecanoylphorbol-13-acetate (TPA) and in a temporally dependent manner, with conversion of a high to low mobility band shift occurring after a 12-h exposure to TPA. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
4 After a 72-h exposure, AP-1 binding activity was maximally increased by 1 nM TPA and remained elevated to a similar degree even after treatment with 600 nM TPA. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
5 After a 72-h exposure, AP-1 binding activity was maximally increased by 1 nM TPA and remained elevated to a similar degree even after treatment with 600 nM TPA. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
6 Enhanced AP-1 binding activity was dependent upon continuous exposure to TPA and was not secondary to differentiation. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
7 A 72-h treatment with one nM TPA maximally increased expression of c-jun, krox-24, and jun-B mRNA transcripts. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens