Title : A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments.

Pub. Date : 1994 Apr

PMID : 8163542






1 Functional Relationships(s)
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1 To explore the role of rab1 we have analyzed the function of a mutant (rab1a[S25N]) containing a substitution which perturbs Mg2+ coordination and reduces the affinity for GTP, resulting in a form which is likely to be restricted to the GDP-bound state. Guanosine Triphosphate RAB1A, member RAS oncogene family Homo sapiens