Title : Mutagenesis rescues spermine and Zn2+ potentiation of recombinant NMDA receptors.

Pub. Date : 1994 Apr

PMID : 8161453






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 NR1 subunits with an N-terminal insert (termed N1) form receptors in Xenopus oocytes with greatly reduced potentiation by spermine and Zn2+. Zinc glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
2 The positively charged N1 may increase NMDA currents by causing a conformational change similar to that produced by spermine and Zn2+ in NR1 receptors lacking N1. Zinc glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis