Title : Ceramide does not mediate the effect of tumour necrosis factor alpha on superoxide generation in human neutrophils.

Pub. Date : 1994 Mar 15

PMID : 8141790






1 Functional Relationships(s)
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1 As it has been reported that ceramide might act as a second messenger to mediate many of the effects of TNF alpha, the effects of exogenous sphingomyelinase and the cell-permeable ceramide analogue, C2- ceramide, on production of superoxide anions, induction of priming in response to formylmethionyl-leucyl-phenylalanine, and cell-shape change were examined. Ceramides tumor necrosis factor Homo sapiens