Title : Reactive oxygen-dependent DNA damage resulting from the oxidation of phenolic compounds by a copper-redox cycle mechanism.

Pub. Date : 1994 Apr 1

PMID : 8137307






1 Functional Relationships(s)
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1 In addition, the induced DNA strand breaks could be inhibited by bathocuproinedisulfonic acid, a Cu(I)-specific chelator, or catalase indicating that a Cu(II)/Cu(I) redox cycle and H2O2 generation are two major determinants involved in the observed DNA damage. bathocuproine sulfonate catalase Homo sapiens