Title : Involvement of nitroxyl (HNO) in the cyanamide-induced vasorelaxation of rabbit aorta.

Pub. Date : 1994 Mar 2

PMID : 8135870






1 Functional Relationships(s)
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1 Since the oxidation of cyanamide by catalase/H2O2 had been shown previously to lead to nitroxyl (HNO) generation via the intermediate N-hydroxycyanamide, and aortic ring relaxation was inhibited by the catalase inhibitor, 3-aminotriazole, HNO appears to be responsible for the vasorelaxation mediated by cyanamide. Hydrogen Peroxide catalase Oryctolagus cuniculus