Title : Production of nitric oxide and superoxide by activated macrophages and killing of Leishmania major.

Pub. Date : 1994 Mar

PMID : 8125136






3 Functional Relationships(s)
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1 We now show that murine macrophages activated with zymosan and interferon-gamma (ZYM/IFN-gamma) produced both superoxide (peaking 1-2 h after stimulation, then rapidly declining) and NO (barely detectable at 6 h, peaking by 24 h). Superoxides interferon gamma Mus musculus
2 We now show that murine macrophages activated with zymosan and interferon-gamma (ZYM/IFN-gamma) produced both superoxide (peaking 1-2 h after stimulation, then rapidly declining) and NO (barely detectable at 6 h, peaking by 24 h). Superoxides interferon gamma Mus musculus
3 Macrophages activated with ZYM alone produced only superoxide, while stimulation with lipopolysaccharide (LPS) and IFN-gamma induced NO but not superoxide. Superoxides interferon gamma Mus musculus