Pub. Date : 1993 May 25
PMID : 8098706
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | After sporulation of diploid disruptants, spores containing the disrupted acc1 allele failed to enter vegetative growth, despite fatty acid supplementation, suggesting that acetyl-CoA carboxylase activity is essential for a process other than de novo fatty acid synthesis and that only a single functional copy of the ACC1 gene exists. | Fatty Acids | acetyl-CoA carboxylase ACC1 | Saccharomyces cerevisiae S288C |
| 2 | After sporulation of diploid disruptants, spores containing the disrupted acc1 allele failed to enter vegetative growth, despite fatty acid supplementation, suggesting that acetyl-CoA carboxylase activity is essential for a process other than de novo fatty acid synthesis and that only a single functional copy of the ACC1 gene exists. | Fatty Acids | acetyl-CoA carboxylase ACC1 | Saccharomyces cerevisiae S288C |
| 3 | ACC1 transcription was repressed 3-fold by lipid precursors, inositol and choline, and was also controlled by regulatory factors Ino2p, Ino4p, and Opi1p, providing evidence that the key step of fatty acid synthesis is regulated in conjunction with phospholipid synthesis at the level of gene expression. | Fatty Acids | acetyl-CoA carboxylase ACC1 | Saccharomyces cerevisiae S288C |