Title : Lack of role of endothelium-derived relaxing factor in effects of alpha-adrenergic agonists in cutaneous veins in humans.

Pub. Date : 1993 Feb

PMID : 8095374






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In some blood vessels, the alpha 2-adrenergic agonist clonidine simultaneously activates vasoconstrictive alpha-adrenoceptors on smooth muscle cells and endothelial alpha 2-adrenoceptors mediating release of endothelium-derived relaxing factor (EDRF), with the net vascular response representing a balance between these two counteracting pathways. Clonidine alpha hemoglobin stabilizing protein Homo sapiens
2 To investigate whether clonidine"s modest constrictor effect in human veins is due to simultaneous release of EDRF, the dorsal hand vein compliance technique was used to measure vascular responses in healthy volunteers. Clonidine alpha hemoglobin stabilizing protein Homo sapiens